Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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706
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720
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707
Tocris Bioscience™ SR 57227 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 77145-61-0 Molecular Formula: C10H15Cl2N3
| CAS | 77145-61-0 |
|---|---|
| Molecular Formula | C10H15Cl2N3 |
708
Tocris Bioscience™ (±)-Epibatidine
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CAS: 148152-66-3 Molecular Formula: C11H13ClN2
| CAS | 148152-66-3 |
|---|---|
| Molecular Formula | C11H13ClN2 |
709
Tocris Bioscience™ Pomalidomide 4'-PEG1-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
710
Tocris Bioscience™ SJ 6986
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Molecular glue; induces degradation of GSPT1/2
| Target | Molecular Glues |
|---|---|
| CAS | 2765625-93-0 |
| Purity | 0.98 |
| Chemical Name or Material | N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H14F3N3O7S |
711
Tocris Bioscience™ AC 265347
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CaSR biased allosteric modulator
| CAS | 1253901-26-6 |
|---|---|
| Chemical Name or Material | α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H17NOS |
| Formula Weight | Observed MW: 283.39 |
| Assay Percent Range | >99% |
712
Tocris Bioscience™ MIRA-1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 72835-26-8 Molecular Formula: C8H9NO4
| CAS | 72835-26-8 |
|---|---|
| Molecular Formula | C8H9NO4 |
713
Tocris Bioscience™ Amlexanox
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 68302-57-8 Molecular Formula: C16H14N2O4
| CAS | 68302-57-8 |
|---|---|
| Molecular Formula | C16H14N2O4 |
714
Tocris Bioscience™ BI 9564
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective BRD9 and BRD7 inhibitor; orally active
715
Tocris Bioscience™ DBHDA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Reagent for synthetic biology; converts cysteine to dehydroalanine
716
Tocris Bioscience™ Cinacalcet hydrochloride
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Low molecular weight, organic compound that may help regulate biological process.
| Target | Calcium-Sensing Receptor |
|---|---|
| CAS | 364782-34-3 |
| Product Type | Inhibitor |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22F3N.HCl |
| Formula Weight | 393.87g/mol |
717
Tocris Bioscience™ PP 242
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Dual mTORC1/mTORC2 inhibitor
| CAS | 1092351-67-1 |
|---|---|
| Chemical Name or Material | 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H16N6O |
| Formula Weight | Observed MW: 308.34 |
| Assay Percent Range | >98% |
718
Tocris Bioscience™ AG 1478 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 170449-18-0 Molecular Formula: C16H15Cl2N3O2
| CAS | 170449-18-0 |
|---|---|
| Molecular Formula | C16H15Cl2N3O2 |
719
Tocris Bioscience™ VH 032 amide-alkylC7-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VHL ligand with alkyl linker and terminal amine for onward chemistry
720
Tocris Bioscience™ Ruxolitinib
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Potent and selective JAK1/JAK2 inhibitor; orally bioavailable